Study/Year

Mean Age (years)

No. of Eyes

Follow up

Reduction in Mean Shpere

Reduction in Mean Cylinder

Improvement in S Eq.

Reduction in Average K value

Current Study/2011

Group 1

13.55

20

6 months

(worse 1.86D)

1.16D

(Worse 1.28D)

0.34D

Group 2

23.95

21

6 months

0.74D

0.19D

0.9D

1.16D

Wollensak et al. [20] /2003

32.13

23

23.2 months

NA

NA

1.14D

2.01D in 70% eyes

Raiskup-Wolf et al. [18] /2008*

>18

241

12 months

NA

0.93D (in 50% eyes)

Stable i.e. within ± 0.50D in 36%

NA

1.46D in 56% eyes.

Stable i.e. within ± 0.50D in 30%

Vinciguerra et al. [21] /2009

24 - 52

(Range)

28

12 months

0.28D

0.26D

0.41D

0.58D at 6 months 6.07D at 1 year

Caporossi et al. [17] /2010

(The Siena Eye Cross Study)

10 - 40

(Range)

44

52.4 months

1.62D at 1 year

0.52D at 1year

1.87 D at 1 year

1.96D at 1 year

Hersh et al. [22] /2011

≥14 yrs

49

12 months

NA

0.08D

0.85D

1.5D